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Dopamine metabolism pathway

          Dopamine uses

        1. Dopamine uses
        2. Dopamine side effects
        3. Mao enzyme supplement
        4. Mao enzyme function
        5. Dopamine function
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          Monoamine oxidase

          Family of enzymes

          Protein family

          Monoamine oxidases (MAO) (EC1.4.3.4) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group.[1][2] They are found bound to the outer membrane of mitochondria in most cell types of the body.

          The first such enzyme was discovered in 1928 by Mary Bernheim in the liver and was named tyramine oxidase.[3][4] The MAOs belong to the protein family of flavin-containing amine oxidoreductases.[5]

          MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters.

          Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.[6]

          Subtypes and tissue distribution

          In humans there are two types of MAO: MAO-A and MAO-B.[7]